Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway

  1. Janet Martha Blatny
  1. Norwegian Defence Research Establishment FFI, Kjeller, Norway

ABSTRACT

Here, we report the complete genome sequences of Legionella pneumophila isolates from two collocated outbreaks of Legionnaires’ disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. One clinical and two environmental isolates were sequenced from each outbreak. The genome of all six isolates consisted of a 3.36 Mb-chromosome, while the 2005 genomes featured an additional 68 kb-episome sharing high sequence similarity with the L. pneumophila Lens plasmid. All six genomes contained multiple mobile genetic elements including novel combinations of type-IVA secretion systems. A comparative genomics study will be launched to resolve the genetic relationship between the L. pneumophila isolates.

FOOTNOTES

  • Address correspondence to Marius Dybwad, marius.dybwad{at}ffi.no.
  • Citation Dybwad M, Aarskaug T, Fykse E-M, Henie Madslien E, Blatny JM. 2016. Complete genome sequences of six Legionella pneumophila isolates from two collocated outbreaks of Legionnaires’ disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. Genome Announc 4(6):e01367-16. doi:10.1128/genomeA.01367-16.

  • Received 13 October 2016.
  • Accepted 24 October 2016.
  • Published 15 December 2016.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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